For the seminar on the 7th of December at 11 am Sofya Marchenko invited Pauline Hiort (PhD student from Prof. Dr. Bernhard Renard Group at the HPI) to talk about her research. If you are interested in joining write an e-Mail to compcancer at charite dot de to receive the zoom link.
DrDimont: explainable drug response prediction from differential analysis of multi-omics networks
The recent publication explained a novel method for condition-specific molecular networks from correlation within an omics layer that are then reduced and combined into heterogeneous, multi-omics molecular networks, which allows to predict drug responses. To demonstrate the efficiency the method, it is applied to breast cancer patients’ samples containing transcriptomics, proteomics, phosphosites and metabolomics measurements and compares drug response between estrogen receptor positive and receptor negative patients.